diff --git a/.agents/skills/multi-agent-mux-create/scripts/create_session.sh b/.agents/skills/multi-agent-mux-create/scripts/create_session.sh
index b9a859b..455757e 100755
--- a/.agents/skills/multi-agent-mux-create/scripts/create_session.sh
+++ b/.agents/skills/multi-agent-mux-create/scripts/create_session.sh
@@ -148,11 +148,29 @@ if [ -n "$ISOLATION_ROOT" ]; then
   ISO_ENV_PREFIX="$(isolation_env_prefix "$AGENT" "$ISOLATION_ROOT")"
   ISO_CMD_ARGS="$(isolation_cmd_args "$AGENT" "$ISOLATION_ROOT")"
 fi
+
+# Resolve absolute path of the agent command to prevent tmux PATH inheritance issues (especially on macOS)
+RESOLVED_BIN="$AGENT"
+if [ "$AGENT" = "cline" ]; then
+  if command -v cline >/dev/null 2>&1; then
+    RESOLVED_BIN="$(command -v cline)"
+  fi
+else
+  if command -v "$AGENT" >/dev/null 2>&1; then
+    RESOLVED_BIN="$(command -v "$AGENT")"
+  fi
+fi
+
+# On macOS, clear quarantine attribute for the agent binary to prevent Gatekeeper hangs
+if [ "$(uname)" = "Darwin" ] && [ -f "$RESOLVED_BIN" ]; then
+  xattr -d com.apple.quarantine "$RESOLVED_BIN" 2>/dev/null || true
+fi
+
 case "$AGENT" in
-  claude) CMD_FULL="${ISO_ENV_PREFIX}claude --dangerously-skip-permissions" ;;
-  agy)    CMD_FULL="${ISO_ENV_PREFIX}agy --dangerously-skip-permissions" ;;
-  hermes) CMD_FULL="${ISO_ENV_PREFIX}hermes" ;;
-  cline)  CMD_FULL="cline -i${ISO_CMD_ARGS:+ $ISO_CMD_ARGS}" ;;
+  claude) CMD_FULL="${ISO_ENV_PREFIX}${RESOLVED_BIN} --dangerously-skip-permissions" ;;
+  agy)    CMD_FULL="${ISO_ENV_PREFIX}${RESOLVED_BIN} --dangerously-skip-permissions" ;;
+  hermes) CMD_FULL="${ISO_ENV_PREFIX}${RESOLVED_BIN}" ;;
+  cline)  CMD_FULL="${RESOLVED_BIN} -i${ISO_CMD_ARGS:+ $ISO_CMD_ARGS}" ;;
 esac
 
 spawn() {
diff --git a/.agents/skills/multi-agent-mux-resume/scripts/resume_session.sh b/.agents/skills/multi-agent-mux-resume/scripts/resume_session.sh
index 6dfd038..294d663 100755
--- a/.agents/skills/multi-agent-mux-resume/scripts/resume_session.sh
+++ b/.agents/skills/multi-agent-mux-resume/scripts/resume_session.sh
@@ -87,12 +87,29 @@ if [ -n "$ISO_ROOT" ]; then
   echo "Re-applying isolation: root=$ISO_ROOT env=$ISO_ENV args=$ISO_ARGS"
 fi
 
+# Resolve absolute path of the agent command to prevent tmux PATH inheritance issues (especially on macOS)
+RESOLVED_BIN="$AGENT"
+if [ "$AGENT" = "cline" ]; then
+  if command -v cline >/dev/null 2>&1; then
+    RESOLVED_BIN="$(command -v cline)"
+  fi
+else
+  if command -v "$AGENT" >/dev/null 2>&1; then
+    RESOLVED_BIN="$(command -v "$AGENT")"
+  fi
+fi
+
+# On macOS, clear quarantine attribute for the agent binary to prevent Gatekeeper hangs
+if [ "$(uname)" = "Darwin" ] && [ -f "$RESOLVED_BIN" ]; then
+  xattr -d com.apple.quarantine "$RESOLVED_BIN" 2>/dev/null || true
+fi
+
 # Determine CMD_FULL with isolation applied
 case "$AGENT" in
-  claude) CMD_FULL="claude --dangerously-skip-permissions -r $UUID" ;;
-  agy)    CMD_FULL="agy --dangerously-skip-permissions --conversation $UUID" ;;
-  hermes) CMD_FULL="hermes --resume $UUID" ;;
-  cline)  CMD_FULL="cline -i --id $UUID" ;;
+  claude) CMD_FULL="${RESOLVED_BIN} --dangerously-skip-permissions -r $UUID" ;;
+  agy)    CMD_FULL="${RESOLVED_BIN} --dangerously-skip-permissions --conversation $UUID" ;;
+  hermes) CMD_FULL="${RESOLVED_BIN} --resume $UUID" ;;
+  cline)  CMD_FULL="${RESOLVED_BIN} -i --id $UUID" ;;
 esac
 
 # Prepend env prefix and append command args (T4)